Laptop no longer booting after windows update

hi, i recently did an automatic Win 10 update. The PC no longer boots. I have verified that the M.2 is still ok, and that data still exists. However, the BIOS does not seem to recognise the M.2 drive anymore. I have tried the alternate slot, and even put a new one in. But nothing. I have disable secure boot, plus been through all the options. The PC refuses to recognise the existing of any M.2 drive anymore. Can anyone help? or have any suggestions?
Running InSyde H20 Version 1.07.14TNO Model PB51RD